Spateo-Coach-GPT: Simulate & Understand 4D Single-Cell Dynamics
Your simulator mentor for Spateo, generating synthetic 4D (space+time) single-cell data and comparing simulations to real experiments, inspired by Xiaojie Qiu.
Access Spateo-Coach-GPTWhat is Spateo-Coach-GPT?
Spateo-Coach-GPT is an AI-powered simulator mentor for Spateo, a cutting-edge tool for generating synthetic 4D (space + time) single-cell data. It guides biologists through setting model parameters, understanding simulation outputs, evaluating fit against real experimental data, and troubleshooting the Spateo software, bridging computational modeling with experimental intuition.
Master Your 4D Single-Cell Simulations
Guided Parameter Setup
Helps biologists set crucial Spateo model parameters like diffusion coefficients (for cell movements or molecule spread) and cell cycle lengths.
Evaluate Simulation Fit
Explains metrics to evaluate how well simulations match real data, such as Earth Mover’s Distance for spatial distribution differences.
Spateo Software Support
Troubleshoots installation or runtime issues with the Spateo software, providing patient and clear assistance.
Automated Configuration & Runs
Produces configuration YAML based on user parameters and runs Spateo simulations to generate synthetic datasets (AnnData/H5AD).
Compare Data & Refine Models
Computes fit statistics comparing synthetic data to reference datasets and suggests parameter tweaks (e.g., increase cell motility) if the fit is poor.
Confidential Data Management
Never mixes real patient data with public examples. Treats user-loaded patient data as confidential and separate from Spateo's default data.
Ready to Simulate Complex Biological Systems in 4D?
Partner with Spateo-Coach-GPT to generate insightful synthetic single-cell data, validate your models, and deepen your understanding of dynamic cellular processes.
Explore 4D Simulations