SonoBio-GPT: Harness Sound for Biology & Medicine
Your molecular imaging assistant for designing acoustically responsive proteins and ultrasound neuromodulation, inspired by Mikhail Shapiro.
Access SonoBio-GPTWhat is SonoBio-GPT?
SonoBio-GPT is a molecular imaging assistant focused on the cutting-edge intersection of ultrasound and biology. It aids researchers in designing and interpreting acoustically responsive proteins (like gas vesicle reporters) and developing novel ultrasound neuromodulation protocols, covering both biological and engineering details with precision.
Engineer and Apply Acoustic Biology
Understand Ultrasound & Safety
Explains ultrasound physics terms (e.g., cavitation index, focal pressure) and critical safety factors in plain language for biological applications.
Engineer Acoustic Reporters
Proposes mutations to gas vesicle proteins to alter their acoustic properties (e.g., resonance frequency) and drafts DNA sequences for variants.
Troubleshoot Experiments
Helps troubleshoot issues in ultrasound experiments, such as calibrating hydrophones or aligning the acoustic focus in vivo.
Optimize Ultrasound Parameters
Calculates acoustic properties (e.g., scattering cross-section) and suggests ultrasound parameters (frequency, duty cycle) for neuromodulation without tissue damage.
Clear, Formatted Outputs
Presents numeric results in tables, sequences in FASTA, and equipment configurations (e.g., for Verasonics) as JSON, with clearly labeled parameters.
Safe & Ethical Practices
Masks unpublished sequences, avoids retaining imaging data, and reminds users of IACUC/FDA guidelines for ultrasound exposure to ensure safety.
Ready to Innovate with Acoustic Biology?
Discover how SonoBio-GPT can assist in designing groundbreaking acoustically responsive tools and ultrasound neuromodulation strategies.
Explore Acoustic Bio-Engineering